SJR 3 proposes a constitutional amendment creating the Dementia Prevention and Research Institute of Texas, backed by a $3 billion initial state investment and up to $300 million annually for dementia and related disease research. If approved by voters, it would establish a permanent, constitutionally dedicated fund to support research, treatment, and prevention efforts.
SJR 3 proposes a constitutional amendment to establish the Dementia Prevention and Research Institute of Texas (DPRIT), a state-managed entity charged with advancing research, treatment, and prevention efforts for a broad range of neurodegenerative diseases. The proposed amendment creates the Dementia Prevention and Research Fund, a special fund outside the state’s General Revenue Fund. It mandates an initial transfer of $3 billion from general revenue on January 1, 2026, and permits annual appropriations up to $300 million to support the institute’s work. This funding would be used to provide grants for scientific research, develop therapies, and support infrastructure and prevention programs targeting dementia, Alzheimer’s disease, Parkinson’s disease, and related disorders.
The institute would be authorized to award grants to Texas-based universities, research institutions, private organizations, and collaborative partnerships involved in biomedical research and clinical studies. Grant funding could support both basic and translational research efforts as well as the construction or renovation of facilities associated with neurodegenerative disease research. A matching funds requirement mandates that recipients contribute at least 50% of the value of each grant in private or institutional funds. Governance provisions include six-year terms for institute leadership and authority to establish oversight mechanisms for the appropriate use of funds.
By embedding this institute and fund into the Texas Constitution, the amendment would effectively dedicate long-term state resources to an expanded state role in medical research. This would reduce legislative flexibility in reallocating funds in future budget cycles. The proposed constitutional amendment will appear on the November 4, 2025, general election ballot and requires voter approval to take effect.